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Article

Early determination in the C. elegans embryo: a gene, cib-1, required to specify a set of stem-cell-like blastomeres.

Development (Cambridge, England) - 1 Jan 1990

Schnabel R, Schnabel H

Abstract excerpt

The early somatic blastomeres founding the tissues in the C. elegans embryo are derived in a stem-cell-like lineage from the P cells. We have isolated maternal effect lethal mutations defining the gene cib-1 in which the P cells, P1-P3, skip a cell cycle and acquire the fates of only their somatic daughters. Therefore, the cib-1 gene is required for the specification of the stem-cell-like fate of these cells. The...

Topics

Alleles
Animals
Blastomeres
Caenorhabditis
Cell Cycle
Genes
Genes, Lethal
Microscopy, Electron
Microscopy, Fluorescence
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2351058
DOI: 10.1242/dev.108.Supplement.107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2351058-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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