Article
Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study.
Human reproduction (Oxford, England) - 1 Jun 2013
Carty C L, Spencer K L, Setiawan V W, Fernandez-Rhodes L, Malinowski J, Buyske S, Young A, Jorgensen N W, Cheng I, Carlson C S, Brown-Gentry K, Goodloe R, Park A, Parikh N I, Henderson B, Le Marchand L, Wactawski-Wende J, Fornage M, Matise T C, Hindorff L A, Arnold A M, Haiman C A, Franceschini N, Peters U, Crawford D C
Abstract excerpt
STUDY QUESTION: Do genetic associations identified in genome-wide association studies (GWAS) of age at menarche (AM) and age at natural menopause (ANM) replicate in women of diverse race/ancestry from the Population Architecture using Genomics and Epidemiology (PAGE) Study? SUMMARY ANSWER: We replicated GWAS reproductive trait single nucleotide polymorphisms (SNPs) in our European descent population and found...
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