Article
Shared genetic factors for age at natural menopause in Iranian and European women.
Human reproduction (Oxford, England) - 1 Jul 2013
Rahmani Maziar, Earp Madalene A, Ramezani Tehrani Fahimeh, Ataee Mehran, Wu Jackson, Treml Martin, Nudischer Ramona, P-Behnami Sara, Perry John R B, Murabito Joanne M, Azizi Fereidoun, Brooks-Wilson Angela
Abstract excerpt
STUDY QUESTION: Do differences in heritable genetic factors explain some of the difference in age at natural menopause (ANM) among populations? SUMMARY ANSWER: One single nucleotide polymorphism (SNP)-ANM association (rs16991615) detected in European women was replicated in Iranian women. WHAT IS KNOWN ALREADY: Genetics plays an important role in ANM, and well-powered genome-wide association studies (GWAS) of ANM...
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