Article

Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

2017-07-12

Abstract excerpt

<h4>ABSTRACT</h4> Traditionally, genetic studies in cancer are focused on somatic mutations found in tumors and absent from the normal tissue. Identification of shared attributes in germline variation could aid discrimination of high-risk from likely benign mutations and narrow the search space for new cancer predisposing genes. Extraordinary progress made in analysis of common variation with GWAS methodology doe...

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Literature Corpus work: 37187227-34d2-5afd-baea-8cf7e1786d5b
DOI: 10.1101/162479

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