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Article

Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice.

Proceedings of the National Academy of Sciences of the United States of America - 28 Oct 2003

Zhang Zhongqiu, Futamura Manabu, Vikis Haris G, Wang Min, Li Jie, Wang Yian, Guan Kun-Liang, You Ming

Abstract excerpt

Pulmonary adenoma susceptibility 1 (Pas1), located on chromosome 6, is the major locus affecting inherited predisposition to lung tumor development in mice. We have fine mapped the Pas1 locus to a region of approximately 0.5 megabases by using congenic strains of mice, constructed by placing the Pas1 region of chromosome 6 from A/J mice onto the genetic background of C57BL/6J mice. Systematic characterization of...

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Identifiers

PMID: 14583591
DOI: 10.1073/pnas.2133947100
PMCID: PMC240671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice.PMID 14583591Read ↗

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