Article
Characterization of the murine Lbx2 promoter, identification of the human homologue, and evaluation as a candidate for Alström syndrome.
Genomics - 1 Jun 2001
Chen F, Collin G B, Liu K C, Beier D R, Eccles M, Nishina P M, Moshang T, Epstein J A
Abstract excerpt
The murine Lbx2 gene is a member of the ladybird family of homeobox genes, which is expressed in the developing urogenital system, eye, and brain. Using transgenic mice, we demonstrate that 9 kb of the 5' flanking region of mouse Lbx2 is able to direct expression of a reporter gene in a tissue-specific manner recapitulating the endogenous expression pattern. This regulatory region provides a novel reagent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.