Article
Generation of a novel functional neuronal circuit in Hoxa1 mutant mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Aug 2001
del Toro E D, Borday V, Davenne M, Neun R, Rijli F M, Champagnat J
Abstract excerpt
Early organization of the vertebrate brainstem is characterized by cellular segmentation into compartments, the rhombomeres, which follow a metameric pattern of neuronal development. Expression of the homeobox genes of the Hox family precedes rhombomere formation, and analysis of mouse Hox mutations revealed that they play an important role in the establishment of rhombomere-specific neuronal patterns. However,...
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