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Article

Mitochondrial respiratory complex function and the phenotypic consequences of dysfunction.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Annesley Sarah J, Carilla-Latorre Sergio, Escalante Ricardo, Fisher Paul R

Abstract excerpt

Dictyostelium provides a well established model system for the study of mitochondrial biology and disease. Mitochondrial dysfunction in Dictyostelium has been generated by knockout of nonessential nuclear genes encoding mitochondrial proteins, by knockout of targeted mitochondrial genes in a subset of the mitochondria, and by knock down of essential nuclear-encoded mitochondrial proteins. The resulting effects on...

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PMID: 23494317
DOI: 10.1007/978-1-62703-302-2_19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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