Article
Mitochondrial mutations impair signal transduction in Dictyostelium discoideum slugs.
Biochemical and biophysical research communications - 8 May 1997
Wilczynska Z, Barth C, Fisher P R
Abstract excerpt
Subpopulations of mutant mitochondria appear to play important roles in degenerative processes associated with aging and are characteristic of many mitochondrial diseases. We have generated mutants carrying plasmid insertions in the Dictyostelium discoideum mitochondrial genome and have shown that phototaxis and thermotaxis in these mutants is more sensitive than growth and division to the presence of a...
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