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Article

The Multifaceted Interactions of Dictyostelium Atg1 with Mitochondrial Function, Endocytosis, Growth, and Development.

Cells - 14 Jul 2024

Sen Melodi Gizem, Sanislav Oana, Fisher Paul Robert, Annesley Sarah Jane

Abstract excerpt

Autophagy is a degradative recycling process central to the maintenance of homeostasis in all eukaryotes. By ensuring the degradation of damaged mitochondria, it plays a key role in maintaining mitochondrial health and function. Of the highly conserved autophagy proteins, autophagy-related protein 1 (Atg1) is essential to the process. The involvement of these proteins in intracellular signalling pathways,...

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Identifiers

PMID: 39056773
DOI: 10.3390/cells13141191
PMCID: PMC11274416

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