Article
Activation and function of TGFβ signalling during Drosophila wing development and its interactions with the BMP pathway.
Developmental biology - 1 May 2013
Hevia Covadonga F, de Celis Jose F
Abstract excerpt
The development of the Drosophila wing disc requires the activities of the BMP and TGFβ signalling pathways. BMP signalling is critical for the correct growth and patterning of the disc, whereas the related TGFβ pathway is mostly required for growth. The BMP and TGFβ pathways share a common co-receptor (Punt) and a nuclear effector (Medea), and consequently it is likely that these pathways can interfere with each...
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