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Article

Biochemical Principles of SMAD Signaling Across the Animal Kingdom

2026-01-02

Abstract excerpt

The TGF-β superfamily, including BMP and TGF-β pathways, regulates fundamental cellular processes such as fate specification, tissue patterning, and stem cell homeostasis across metazoans. The BMP pathway across these diverse animal systems share a conserved intracellular SMAD signaling architecture. The quantitative dynamics of SMAD signaling and regulatory strategies governing pathway activity show a wide range...

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Identifiers and source

Literature Corpus work
e869d8c7-86ad-59d3-9bd1-044ccf350df3
DOI
10.20944/preprints202601.0062.v1
Open publication

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