Article
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling.
Development (Cambridge, England) - 1 Sept 2008
Batut Julie, Schmierer Bernhard, Cao Jing, Raftery Laurel A, Hill Caroline S, Howell Michael
Abstract excerpt
We identify Balpha (PPP2R2A) and Bdelta (PPP2R2D), two highly related members of the B family of regulatory subunits of the protein phosphatase PP2A, as important modulators of TGF-beta/Activin/Nodal signalling that affect the pathway in opposite ways. Knockdown of Balpha in Xenopus embryos or ma...
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