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Article

R-Smad competition controls activin receptor output in Drosophila.

PloS one - 1 Jan 2012

Peterson Aidan J, Jensen Philip A, Shimell MaryJane, Stefancsik Ray, Wijayatonge Ranjula, Herder Rachel, Raftery Laurel A, O'Connor Michael B

Abstract excerpt

Animals use TGF-β superfamily signal transduction pathways during development and tissue maintenance. The superfamily has traditionally been divided into TGF-β/Activin and BMP branches based on relationships between ligands, receptors, and R-Smads. Several previous reports have shown that, in cell culture systems, "BMP-specific" Smads can be phosphorylated in response to TGF-β/Activin pathway activation. Using...

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PMID: 22563507
DOI: 10.1371/journal.pone.0036548
PMCID: PMC3341346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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