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Monitoring Smad Activity In Vivo Using the Xenopus Model System.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Montagner Marco, Martello Graziano, Piccolo Stefano

Abstract excerpt

The embryo of the African clawed frog Xenopus laevis plays a central role in the field of cell and developmental biology. One of the strengths of Xenopus as model system lies in the high degree of conservation between amphibians and mammals in the molecular mechanisms controlling tissue patterning and differentiation. As such, many signaling cascades were first investigated in frog embryos and then confirmed in...

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PMID: 26520129
DOI: 10.1007/978-1-4939-2966-5_15

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