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Article

Mechanisms of oral carcinogenesis induced by dibenzo[a,l]pyrene: an environmental pollutant and a tobacco smoke constituent.

International journal of cancer - 15 Sept 2013

Chen Kun-Ming, Guttenplan Joseph B, Zhang Shang-Min, Aliaga Cesar, Cooper Timothy K, Sun Yuan-Wan, DelTondo Joseph, Kosinska Wieslawa, Sharma Arun K, Jiang Kun, Bruggeman Richard, Ahn Kwangmi, Amin Shantu, El-Bayoumy Karam

Abstract excerpt

We previously reported that dibenzo[a,l]pyrene (DB[a,l]P), the most potent known environmental carcinogen among polycyclic aromatic hydrocarbons (PAH) congeners, is carcinogenic in the oral tissues of mice. We have now developed a new mouse model which employs the oral application of the fjord re...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23483552
DOI: 10.1002/ijc.28152
PMCID: PMC3707976

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23483552-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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