Article
Mutagenesis induced by oral carcinogens in lacZ mouse (MutaMouse) tongue and other oral tissues.
Carcinogenesis - 1 Nov 1999
von Pressentin M M, Kosinska W, Guttenplan J B
Abstract excerpt
Animal models for carcinogenesis of the oral cavity are limited, although this disease is often fatal or disfiguring and its incidence in the USA is approximately 30 000 cases/year. Short-term whole-animal models for this disease should prove valuable in the investigation of factors affecting oral carcinogenesis. In this study we observed that a group of oral carcinogens are clearly mutagenic in the lacZ...
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