Article
Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Jun 2013
Lee J-H, Hachiya A, Shin S-K, Lee J, Gatanaga H, Oka S, Kirby K A, Ong Y T, Sarafianos S G, Folk W R, Yoo W, Hong S P, Kim S-O
Abstract excerpt
Viral genotype assessment is important for effective clinical management of HIV-1 infected patients, especially when access and/or adherence to antiretroviral treatment is reduced. In this study, we describe development of a matrix-assisted laser desorption/ionization-time of flight mass spectrometry-based viral genotyping assay, termed restriction fragment mass polymorphism (RFMP). This assay is suitable for...
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