Article
Analytical and clinical performances of a restriction fragment mass polymorphism assay for detection and genotyping of a wide spectrum of human papillomaviruses.
Journal of medical virology - 1 Mar 2011
Lee Hyo-Pyo, Kim Soo-Ok, Hwang Tae Sook, Bae Jae-Man, Kim Soo Nyung, Kim Jae Won, Hwang Sun Young, Lee Han Sung, Shin Soo-Kyung, Cho Woojae, Hong Sun Pyo
Abstract excerpt
Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry-based restriction fragment mass polymorphism (RFMP) assay was adapted to human papillomavirus (HPV) genotyping. The analytical sensitivity and the clinical utility were evaluated by testing defined HPV genome equivalents and a total of 426 specimens composed of normal cytology, atypical squamous cells of undetermined...
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