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Article

A simple and accurate SNP scoring strategy based on typeIIS restriction endonuclease cleavage and matrix-assisted laser desorption/ionization mass spectrometry.

BMC genomics - 9 Jun 2008

Hong Sun Pyo, Ji Seung Il, Rhee Hwanseok, Shin Soo Kyeong, Hwang Sun Young, Lee Seung Hwan, Lee Soong Deok, Oh Heung-Bum, Yoo Wangdon, Kim Soo-Ok

Abstract excerpt

BACKGROUND: We describe the development of a novel matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF)-based single nucleotide polymorphism (SNP) scoring strategy, termed Restriction Fragment Mass Polymorphism (RFMP) that is suitable for genotyping variations in a simple, accurate, and high-throughput manner. The assay is based on polymerase chain reaction (PCR) amplification and mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Identifiers

PMID: 18538037
DOI: 10.1186/1471-2164-9-276
PMCID: PMC2442615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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