Article
Sensitivity and specificity of the ViroSeq human immunodeficiency virus type 1 (HIV-1) genotyping system for detection of HIV-1 drug resistance mutations by use of an ABI PRISM 3100 genetic analyzer.
Journal of clinical microbiology - 1 Feb 2005
Eshleman Susan H, Crutcher Gillian, Petrauskene Olga, Kunstman Kevin, Cunningham Shawn P, Trevino Christina, Davis Cheryl, Kennedy John, Fairman Jeff, Foley Brian, Kop Joann
Abstract excerpt
The ViroSeq human immunodeficiency virus type 1 (HIV-1) genotyping system is an integrated system for identification of drug resistance mutations in HIV-1 protease and reverse transcriptase (RT). Reagents are included for sample preparation, reverse transcription, PCR amplification, and sequencing. Software is provided to assemble and edit sequence data and to generate a drug resistance report. We determined the...
Topics
- Anti-HIV Agents
- Drug Resistance, Viral
- Genotype
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Microbial Sensitivity Tests
- Mutation