Article
Kinesin-1 acts with netrin and DCC to maintain sensory neuron position in Caenorhabditis elegans.
Genetics - 1 May 2013
Barsi-Rhyne Benjamin J, Miller Kristine M, Vargas Christopher T, Thomas Anthony B, Park Joori, Bremer Martina, Jarecki Jessica L, VanHoven Miri K
Abstract excerpt
The organization of neurons and the maintenance of that arrangement are critical to brain function. Failure of these processes in humans can lead to severe birth defects, mental retardation, and epilepsy. Several kinesins have been shown to play important roles in cell migration in vertebrate systems, but few upstream and downstream pathway members have been identified. Here, we utilize the genetic model organism...
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