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Article

Anatomical plasticity of adult brain is titrated by Nogo Receptor 1.

Neuron - 6 Mar 2013

Akbik Feras V, Bhagat Sarah M, Patel Pujan R, Cafferty William B J, Strittmatter Stephen M

Abstract excerpt

Experience rearranges anatomical connectivity in the brain, but such plasticity is suppressed in adulthood. We examined the turnover of dendritic spines and axonal varicosities in the somatosensory cortex of mice lacking Nogo Receptor 1 (NgR1). Through adolescence, the anatomy and plasticity of ngr1 null mice are indistinguishable from control, but suppression of turnover after age 26 days fails to occur in...

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Identifiers

PMID: 23473316
DOI: 10.1016/j.neuron.2012.12.027
PMCID: PMC3594793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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