Article

Deletion of Neuroligins from Astrocytes Does Not Detectably Alter Synapse Numbers or Astrocyte Cytoarchitecture by Maturity

2023-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Astrocytes perform multifarious roles in the formation, regulation, and function of synapses in the brain, but the mechanisms involved are incompletely understood. Interestingly, astrocytes abundantly express neuroligins, postsynaptic adhesion molecules that function as synaptic organizers by binding to presynaptic neurexins. Here we examined the function of neuroligins in astrocytes with a rigo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cd11e97f-fb6c-53ba-ae6d-b58ebf94659f
DOI: 10.1101/2023.04.10.536254

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deletion of Neuroligins from Astrocytes Does Not Detectably Alter Synapse Numbers or Astrocyte Cytoarchitecture by MaturityDOI 10.1101/2023.04.10.536254Read

Astrocytes prevent abnormal neuronal development in the fragile x mouse.Semantic proximity Read

Phenotypic and functional heterogeneity of GFAP-expressing cells in vitro: differential expression of LeX/CD15 by GFAP-expressing multipotent neural stem cells and non-neurogenic astrocytes.Semantic proximity Read

Control of CNS synapse development by {gamma}-protocadherin-mediated astrocyte-neuron contact.Semantic proximity Read

Control of excitatory and inhibitory synapse formation by neuroligins.Semantic proximity Read

Transgenic techniques for cell ablation or molecular deletion to investigate functions of astrocytes and other GFAP-expressing cell types.Semantic proximity Read

A review on the current neuroligin mouse models.Semantic proximity Read

Neuroligins determine synapse maturation and function.Semantic proximity Read

Astrocytes Grown in Alvetex(®) Three Dimensional Scaffolds Retain a Non-reactive Phenotype.Semantic proximity Read

Ezrin deficiency triggers glial fibrillary acidic protein upregulation and a distinct reactive astrocyte phenotype.Semantic proximity Read

Functions of synapse adhesion molecules neurexin/neuroligins and neurodevelopmental disorders.Semantic proximity Read

Human-Mouse Chimeric Brain Models to Study Human Glial-Neuronal and Macroglial-Microglial InteractionsSemantic proximity Read

Dysregulation of astrocyte extracellular signaling in Costello syndrome.Semantic proximity Read