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Article

5' UTR control of native ERG and of Tmprss2:ERG variants activity in prostate cancer.

PloS one - 1 Jan 2013

Zammarchi Francesca, Boutsalis George, Cartegni Luca

Abstract excerpt

ERG, a member of the ETS transcription factor family, is frequently overexpressed in prostate cancer as a result of its fusion to the androgen-responsive Tmprss2 gene. Different genomic rearrangements and alternative splicing events around the junction region lead to multiple combination of Tmprss2:ERG fusion transcripts that correlate with different tumor aggressiveness, but their specific functions and...

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PMID: 23472063
DOI: 10.1371/journal.pone.0049721
PMCID: PMC3589450

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ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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