Article
ViSEN: methodology and software for visualization of statistical epistasis networks.
Genetic epidemiology - 1 Apr 2013
Hu Ting, Chen Yuanzhu, Kiralis Jeff W, Moore Jason H
Abstract excerpt
The nonlinear interaction effect among multiple genetic factors, i.e. epistasis, has been recognized as a key component in understanding the underlying genetic basis of complex human diseases and phenotypic traits. Due to the statistical and computational complexity, most epistasis studies are limited to interactions with an order of two. We developed ViSEN to analyze and visualize epistatic interactions of both...
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