Article
CINOEDV: a co-information based method for detecting and visualizing n-order epistatic interactions.
BMC bioinformatics - 17 May 2016
Shang Junliang, Sun Yingxia, Liu Jin-Xing, Xia Junfeng, Zhang Junying, Zheng Chun-Hou
Abstract excerpt
BACKGROUND: Detecting and visualizing nonlinear interaction effects of single nucleotide polymorphisms (SNPs) or epistatic interactions are important topics in bioinformatics since they play an important role in unraveling the mystery of "missing heritability". However, related studies are almost limited to pairwise epistatic interactions due to their methodological and computational challenges. RESULTS: We...
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