Article
Analysis of gene-gene interactions.
Current protocols in human genetics - 1 Jul 2011
Gilbert-Diamond Diane, Moore Jason H
Abstract excerpt
The goal of this unit is to introduce gene-gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes. This unit begins with an overview of gene-gene interactions and why they are likely to be common. Then, it reviews several statistical and computational methods for detecting and characterizing genes with effects that are dependent on other genes. The focus...
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