Adjusting for population stratification in a fine scale with principal components and sequencing data.

Abstract excerpt

Population stratification is of primary interest in genetic studies to infer human evolution history and to avoid spurious findings in association testing. Although it is well studied with high-density single nucleotide polymorphisms (SNPs) in genome-wide association studies (GWASs), next-generation sequencing brings both new opportunities and challenges to uncovering population structures in finer scales....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Africa
• Share to Black People
• Share to Cluster Analysis