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Article

Smooth muscle cells of human intracranial aneurysms assume phenotypic features similar to those of the atherosclerotic plaque.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000

Coen Matteo, Burkhardt Karim, Bijlenga Philippe, Gabbiani Giulio, Schaller Karl, Kövari Enikö, Rüfenacht Daniel A, Ruíz Diego San Millán, Pizzolato Giampaolo, Bochaton-Piallat Marie-Luce

Abstract excerpt

OBJECTIVES: Characterize the phenotypic features of smooth muscle cells (SMCs) in the wall of human saccular intracranial aneurysms (sIAs). METHODS AND RESULTS: We investigated by means of immunohistochemistry the expression of the cytoskeletal differentiation markers α-smooth muscle actin (α-SMA), smooth muscle myosin heavy chains (SMMHCs), and smoothelin in 26 sIAs and 15 nonaneurysmal cerebral arteries. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23466011
DOI: 10.1016/j.carpath.2013.01.083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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