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Article

Smooth muscle cell fate and plasticity in atherosclerosis.

Cardiovascular research - 15 Mar 2018

Allahverdian Sima, Chaabane Chiraz, Boukais Kamel, Francis Gordon A, Bochaton-Piallat Marie-Luce

Abstract excerpt

Current knowledge suggests that intimal smooth muscle cells (SMCs) in native atherosclerotic plaque derive mainly from the medial arterial layer. During this process, SMCs undergo complex structural and functional changes giving rise to a broad spectrum of phenotypes. Classically, intimal SMCs are described as dedifferentiated/synthetic SMCs, a phenotype characterized by reduced expression of contractile...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Plaque, Atherosclerotic

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Source

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Identifiers

PMID: 29385543
DOI: 10.1093/cvr/cvy022
PMCID: PMC5852505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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