Article
Circ_0008571 modulates the phenotype of vascular smooth muscle cells by targeting miR-145-5p in intracranial aneurysms.
Biochimica et biophysica acta. Molecular basis of disease - 1 Aug 2024
Lu Zhiwen, Zhu Shijie, Wu Yina, Xu Xiaolong, Li Siqi, Huang Qinghai
Abstract excerpt
BACKGROUND: The dysfunction of human vascular smooth cells (hVSMCs) is significantly connected to the development of intracranial aneurysms (IAs). By suppressing the activity of microRNAs (miRNAs), circular RNAs (circRNAs) participate in IA pathogenesis. Nevertheless, the role of hsa_circ_0008571 in IAs remains unclear. METHODS: circRNA sequencing was used to identify circRNAs from human IA tissues. To determine...
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