Article
Intimal smooth muscle cells of porcine and human coronary artery express S100A4, a marker of the rhomboid phenotype in vitro.
Circulation research - 13 Apr 2007
Brisset Anne C, Hao Hiroyuki, Camenzind Edoardo, Bacchetta Marc, Geinoz Antoine, Sanchez Jean-Charles, Chaponnier Christine, Gabbiani Giulio, Bochaton-Piallat Marie-Luce
Abstract excerpt
We reported that smooth muscle cell (SMC) populations isolated from normal porcine coronary artery media exhibit distinct phenotypes: spindle-shaped (S) and rhomboid (R). R-SMCs are recovered in higher proportion from stent-induced intimal thickening compared with media suggesting that they participate in intimal thickening formation. Our aim was to identify a marker of R-SMCs in vitro and to explore its possible...
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