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Article

Phenotypic transformation of smooth muscle in vasospasm after aneurysmal subarachnoid hemorrhage.

Translational stroke research - 1 Jun 2014

Shimamura Norihito, Ohkuma Hiroki

Abstract excerpt

Differentiated smooth muscle cells (SMC) control vasoconstriction and vasodilation, but they can undergo transformation, proliferate, secret cytokines, and migrate into the subendotherial layer with adverse consequences. In this review, we discuss the phenotypic transformation of SMC in cerebral vasospasm after subarachnoid hemorrhage. Phenotypic transformation starts with an insult as caused by aneurysm rupture:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24323729
DOI: 10.1007/s12975-013-0310-1

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