Article
Polymorphisms in the interleukin-7 receptor α gene and mortality in untreated HIV-infected individuals.
AIDS (London, England) - 19 Jun 2013
Hartling Hans J, Thørner Lise W, Erikstrup Christian, Zinyama Rutendo, Kallestrup Per, Gomo Exnevia, Nielsen Susanne D, Ullum Henrik
Abstract excerpt
OBJECTIVES: Recently, polymorphisms in the gene encoding the interleukin-7 receptor α (IL7Rα) have been shown to influence the CD4 cell count in HIV-infected individuals. The objective of this study was to examine the impact of 10 single nucleotide polymorphisms (SNPs) in or in close proximity to the IL7Rα on mortality among 152 untreated HIV infected in a Zimbabwean cohort. METHODS: Patients were followed...
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