Article
Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults.
AIDS (London, England) - 12 Nov 2007
Erikstrup Christian, Kallestrup Per, Zinyama-Gutsire Rutendo B, Gomo Exnevia, Butterworth Anthony E, Pedersen Bente K, Ostrowski Sisse R, Gerstoft Jan, Ullum Henrik
Abstract excerpt
OBJECTIVES: To evaluate the effect on HIV progression of single nucleotide polymorphisms in promoters of the genes for tumour necrosis factor (TNF)-alpha and interleukin (IL)-10 and known to influence cytokine production. METHODS: Survival was documented for 4.3 years after baseline for 198 HIV-1-infected and 180 HIV-uninfected individuals from the Mupfure Schistosomiasis and HIV Cohort in rural Zimbabwe....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
