Article
Impact of IL-6 and IL-6r variants on HIV-1 susceptibility and progression to AIDS: a case-control study in a Moroccan population.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2024
Haddaji Asmaa, Ouladlahsen Ahd, Lkhider Mustapha, Tanouti Ikram-Allah, Abbadi Islam, Hilmi Soufiane, Bensghir Rajaa, Guessous Fadila, Pineau Pascal, Marhoum El Filali Kamal, Ezzikouri Sayeh
Abstract excerpt
Interleukin-6 (IL-6), a pro-inflammatory cytokine, is an important regulator of the inflammatory immune response. We aimed to assess the association of common single nucleotide polymorphisms (SNPs) in IL-6 (rs1800795 G > C, rs1800797 A > G) and interleukin-6 receptor (IL-6R) (rs2228145 A > C) genes with HIV-1 infection, AIDS progression, and response to treatment. In this case-control study involving 199...
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