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Article

Role of selected genetic variants in lung cancer risk in African Americans.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2013

Spitz Margaret R, Amos Christopher I, Land Susan, Wu Xifeng, Dong Qiong, Wenzlaff Angela S, Schwartz Ann G

Abstract excerpt

INTRODUCTION: Black/white disparities in lung cancer incidence and mortality mandate an evaluation of underlying biological differences. We have previously shown higher risks of lung cancer associated with prior emphysema in African American compared with white patients with lung cancer. METHODS: We therefore evaluated a panel of 1440 inflammatory gene variants in a two-phase analysis (discovery and replication),...

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Identifiers

PMID: 23454887
DOI: 10.1097/JTO.0b013e318283da29
PMCID: PMC3623962

Genes

EXOC2
REV1

Provenance

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