Article
Whole-exome sequencing reveals genetic variability among lung cancer cases subphenotyped for emphysema.
Carcinogenesis - 1 Feb 2016
Lusk Christine M, Wenzlaff Angela S, Dyson Greg, Purrington Kristen S, Watza Donovan, Land Susan, Soubani Ayman O, Gadgeel Shirish M, Schwartz Ann G
Abstract excerpt
Lung cancer continues to be a major public health challenge in the United States despite efforts to decrease the prevalence of smoking; outcomes are especially poor for African-American patients compared to other races/ethnicities. Chronic obstructive pulmonary disease (COPD) co-occurs with lung cancer frequently, but not always, suggesting both shared and distinct risk factors for these two diseases. To identify...
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