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Article

COPD-dependent effects of genetic variation in key inflammation pathway genes on lung cancer risk.

International journal of cancer - 1 Aug 2020

Watza Donovan, Lusk Christine M, Dyson Gregory, Purrington Kristen S, Wenzlaff Angela S, Neslund-Dudas Christine, Soubani Ayman O, Gadgeel Shirish M, Schwartz Ann G

Abstract excerpt

Genome-wide association studies (GWAS) have identified several loci contributing to lung cancer and COPD risk independently; however, inflammation-related pathways likely harbor additional lung cancer risk-associated variants in biologically relevant immune genes that differ dependent on COPD. We selected single nucleotide polymorphisms (SNPs) proximal to 2,069 genes within 48 immune pathways. We modeled the...

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Identifiers

PMID: 31709530
DOI: 10.1002/ijc.32780
PMCID: PMC7211135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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