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Article

Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia.

Leukemia research - 1 May 2013

Nousome Darryl, Lupo Philip J, Okcu M Fatih, Scheurer Michael E

Abstract excerpt

Discovering genetic predictors of childhood acute lymphoblastic leukemia (ALL) necessitates the evaluation of novel factors including maternal genetic effects, which are a proxy for the intrauterine environment, and robust epidemiologic study designs. Therefore, we evaluated five maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood ALL among 120 case-parent triads. Two of the five...

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Source

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Identifiers

PMID: 23433810
DOI: 10.1016/j.leukres.2013.01.020
PMCID: PMC3622777

Genes

EPHX1
GSTA4
GSTM3
GSTM4
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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