Article
Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia.
Cancer causes & control : CCC - 1 Aug 2012
Chokkalingam Anand P, Metayer Catherine, Scelo Ghislaine A, Chang Jeffrey S, Urayama Kevin Y, Aldrich Melinda C, Guha Neela, Hansen Helen M, Dahl Gary V, Barcellos Lisa F, Wiencke John K, Wiemels Joseph L, Buffler Patricia A
Abstract excerpt
BACKGROUND: Recent studies suggest that environmental exposures to pesticides, tobacco, and other xenobiotic chemicals may increase risk of childhood acute lymphoblastic leukemia (ALL). We sought to evaluate the role of genes involved in xenobiotic transport and metabolism in childhood ALL risk, both alone and in conjunction with household chemical exposures previously found to be associated with childhood ALL...
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