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Article

Maternal smoking during pregnancy, genetic polymorphisms of metabolic enzymes, and childhood acute leukemia: the ESCALE study (SFCE).

Cancer causes & control : CCC - 1 Feb 2012

Bonaventure Audrey, Goujon-Bellec Stéphanie, Rudant Jérémie, Orsi Laurent, Leverger Guy, Baruchel André, Bertrand Yves, Nelken Brigitte, Pasquet Marlène, Michel Gérard, Sirvent Nicolas, Bordigoni Pierre, Ducassou Stéphane, Rialland Xavier, Zelenika Diana, Hémon Denis, Clavel Jacqueline

Abstract excerpt

PURPOSE: This study explored interactions between prenatal exposure to maternal smoking and polymorphisms in metabolic genes in the risk of childhood acute leukemia (AL). METHODS: The data were generated by the ESCALE study, which included 764 AL cases and 1,681 controls in 2003-2004. The data on maternal smoking during pregnancy were obtained by standardized telephone interview of the cases' and controls'...

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Identifiers

PMID: 22200898
DOI: 10.1007/s10552-011-9882-9

Genes

EPHX1
NAT2
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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