Article
The potential role of APOBEC3G in limiting replication of hepatitis B virus.
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology - 1 Dec 2012
Mohamadkhani Ashraf, Pourdadash Akbar, Tayebi Sirous, Estakhri Arezoo, Nazem Habibollah, Sotoudeh Masoud, Poustchi Hossein
Abstract excerpt
BACKGROUND AND STUDY AIMS: Recent findings introduced APOBEC3G (A3G) as a host factor that blocks viral replication. It induces G to A hypermutations in viral DNA at the step of reverse transcription and in response to interferon. This study aimed to investigate the expression of liver A3G protein in association with both replication of hepatitis B virus (HBV) and frequency of G to A mutations in BCP (basal core...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
