Article
Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection.
British journal of cancer - 4 Dec 2012
Chu C-M, Lin C-C, Chen Y-C, Jeng W-J, Lin S-M, Liaw Y-F
Abstract excerpt
BACKGROUND: As most cases of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) have concurrent cirrhosis, viral factors identified to be associated with HCC might be related to cirrhosis rather than HCC. METHODS: Hepatitis B virus DNA levels, genotypes and precore/basal core promoter (BCP) mutants were compared between cirrhotic HCC and non-cirrhotic HCC patients. Age- and sex-matched case-control...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
