Article
Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail.
Brain pathology (Zurich, Switzerland) - 1 Mar 2013
Fontebasso Adam M, Liu Xiao-Yang, Sturm Dominik, Jabado Nada
Abstract excerpt
Primary brain tumors occur in 8 out of 100 000 people and are the leading cause of cancer-related death in children. Among brain tumors, high-grade astrocytomas (HGAs) including glioblastoma multiforme (GBM) are aggressive and are lethal human cancers. Despite decades of concerted therapeutic efforts, HGAs remain essentially incurable in adults and children. Recent discoveries have revolutionized our...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
