Article
Selective repair of specific chromatin domains in UV-irradiated cells from xeroderma pigmentosum complementation group C.
Mutation research - 1 May 1990
Kantor G J, Barsalou L S, Hanawalt P C
Abstract excerpt
The limited DNA-excision repair in UV-irradiated nondividing fibroblasts from xeroderma pigmentosum complementation group C (XP-C) occurs in localized chromatin regions generating large DNA segments (at least 30-70 kb) free of pyrimidine dimers. A genomic fraction enriched for this DNA was isolated on the basis of the larger size of the repaired fragments after UV-endonuclease treatment and screened for specific...
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