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Article

Heterogeneity of DNA repair at the gene level.

Mutation research - 1 Apr 1991

Hanawalt P C

Abstract excerpt

Overall genomic DNA repair efficiencies do not necessarily correlate with cellular sensitivities to radiation and other DNA-damaging agents. My colleagues and I have developed experimental approaches to measure DNA lesions and their repair in defined DNA sequences and we have discovered that for some types of damage, such as the cyclobutane pyrimidine dimers produced in DNA by ultraviolet light (UV), repair is...

Topics

Animals
DNA Damage
DNA Probes
DNA Repair
Models, Biological
Mutation
Proto-Oncogenes
Pyrimidine Dimers

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2011138
DOI: 10.1016/0027-5107(91)90016-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2011138-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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