Article
Higher frequencies of GARP(+)CTLA-4(+)Foxp3(+) T regulatory cells and myeloid-derived suppressor cells in hepatocellular carcinoma patients are associated with impaired T-cell functionality.
Cancer research - 15 Apr 2013
Kalathil Suresh, Lugade Amit A, Miller Austin, Iyer Renuka, Thanavala Yasmin
Abstract excerpt
The extent to which T-cell-mediated immune surveillance is impaired in human cancer remains a question of major importance, given its potential impact on the development of generalized treatments of advanced disease where the highest degree of heterogeneity exists. Here, we report the first globa...
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