Current Insights into the Role of Peripheral Blood Immune Cell Phenotypes in Resistance to Cancer Therapies.

Abstract excerpt

Peripheral blood mononuclear cell (PBMC) immunophenotyping has emerged as a promising non-invasive approach to characterize systemic immune alterations in cancer and to identify biomarkers associated with treatment response and resistance. However, current evidence remains fragmented and predominantly descriptive, with substantial heterogeneity in study design, immunophenotyping methodologies, and patient...

Topics

• Humans
• Neoplasms
• Drug Resistance, Neoplasm
• Phenotype
• Leukocytes, Mononuclear
• Immunophenotyping
• T-Cell Exhaustion